COMPARATIVE CHARACTERIZATION OF PORINS FROM SALMONELLA TYPHIO-901 AND SALMONELLA TYPHIMURIUM RA-30

نویسندگان

  • BAHMAN TABARAIE From the Department of Bacterial Vaccines & Antigens, Production & Research Complex, Pasteur Institute of Iran, Tehran, I.R. Iran
  • BALK SHARMA the Departments of Internal Medicine and Experimental Medicine & Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
  • HOJAT AHMADI From the Department of Bacterial Vaccines & Antigens, Production & Research Complex, Pasteur Institute of Iran, Tehran, I.R. Iran
  • MEHDI NEJATI From the Department of Bacterial Vaccines & Antigens, Production & Research Complex, Pasteur Institute of Iran, Tehran, I.R. Iran
  • NIRMAL K. GANGULY the Departments of Internal Medicine and Experimental Medicine & Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
  • PARVEEN SHARMA the Departments of Internal Medicine and Experimental Medicine & Biotechnology, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India.
چکیده مقاله:

Porins from Salmonella typhi 0-901 and Salmonella typhimurium Ra-30 were characterized and compared. The elution profile of porins from these salmonella species on Sepharose-48 and HPLC appear to be very similar. The findings were confirmed by the electrophoretic pattern which showed three types of porins, i.e. OmpC, OmpD and OmpF in both species. These porins appear to be similar, if not identical, as the LPS-absorbed antiporin antibodies reacted with homologous as well as heterologous antigens. The results of this study favour the use of porins as a common immunogen to control salmonellosis since porin patterns were found to be quite similar among the serotypes of salmonellae, unlike other enterobacterial species.

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comparative characterization of porins from salmonella typhio-901 and salmonella typhimurium ra-30

porins from salmonella typhi 0-901 and salmonella typhimurium ra-30 were characterized and compared. the elution profile of porins from these salmonella species on sepharose-48 and hplc appear to be very similar. the findings were confirmed by the electrophoretic pattern which showed three types of porins, i.e. ompc, ompd and ompf in both species. these porins appear to be similar, if not ident...

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عنوان ژورنال

دوره 14  شماره 2

صفحات  161- 168

تاریخ انتشار 2000-08

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